SCHEMBL294104

SCHEMBL294104

CCCC[n+]1cccc(CO)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HSP90AA1 P07900 2/20 0.44
HTT P42858 2/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
RAD52 P43351 1/20 0.44
APAF1 O14727 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
XBP1 P17861 1/20 0.44
BLM P54132 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ABCB11 O95342 1/20 0.41
ESR1 P03372 1/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300958 0.92 LMNA (0.47) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
Bromide SCHEMBL20544414 0.87 KDM4E (0.58) KDM4EACHE
SCHEMBL21629882 0.86 HDAC1 (0.46) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL29724068 0.86 HDAC1 (0.46) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL29659675 0.85 HTT (0.46) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL902375 0.85 HTT (0.46) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL5330510 0.85 LMNA (0.38) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL29974913 0.85 LMNA (0.38) LMNAHSP90AA1HTTKDM4ESMN1; SMN2
SCHEMBL5298519 0.84 HDAC1 (0.53) LMNAHSP90AA1HTTSMN1; SMN2RAD52
SCHEMBL5305795 0.84 HDAC1 (0.49) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3835386-B1 TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2023-11-15 EP claimed
EP-3835383-B1 ONE COMPONENT (1K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2023-04-12 EP claimed
EP-3835381-B1 TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2023-02-08 EP claimed
EP-2276917-B1 DEVICE, SYSTEM AND METHOD FOR PROVIDING A REDUCING AGENT FOR A SYSTEM FOR THE SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES BOSCH GMBH ROBERT (DE) 2012-03-14 EP claimed