Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27001280 | 1.00 | HSP90AB1 (0.53) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL14115300 | 0.91 | HSP90AB1 (0.62) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL1115348 | 0.87 | HSP90AB1 (0.62) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL14420085 | 0.84 | HSP90AB1 (0.55) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL1559919 | 0.83 | HSP90AB1 (0.53) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL27001282 | 0.83 | HSP90AB1 (0.53) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL26731080 | 0.81 | HSP90AB1 (0.51) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL21891794 | 0.81 | HSP90AB1 (0.75) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL25460742 | 0.81 | HSP90AB1 (0.55) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL30415830 | 0.81 | HSP90AB1 (0.55) | HSP90AB1CYP4F2CYP4A11GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208452-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022051634-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2022-03-10 | — | — | WO | disclosed |