Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115348 | 0.87 | HSP90AB1 (0.62) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL8257613 | 0.87 | HSP90AB1 (0.62) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL8360725 | 0.87 | HSP90AB1 (0.62) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL30739013 | 0.83 | MAOB (0.40) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1500686 | 0.83 | MAOB (0.40) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27001280 | 0.83 | HSP90AB1 (0.53) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL29410751 | 0.83 | HSP90AB1 (0.53) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL15378035 | 0.82 | MTNR1A (0.45) | HSP90AB1CYP4F2CYP4A11ALDH1A1KMT2A | |
| SCHEMBL38656006 | 0.81 | CA12 (0.36) | HSP90AB1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL34471006 | 0.81 | TSHR (0.41) | KMT2AMEN1NPC1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125401-A1 | BORON-CONTAINING RHO KINASE INHIBITORS | PERCIPIAD, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260116848-A1 | Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists | CARMOT THERAPEUTICS INC. (US) | 2026-04-30 | — | — | US | disclosed |
| US-20250388601-A1 | Compounds, Compositions and Methods | DENALI THERAPEUTICS INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-12479866-B2 | Boron-containing rho kinase inhibitors | PERCIPIAD, INC. | 2025-11-25 | — | — | US | disclosed |
| EP-3999072-B1 | BORON-CONTAINING RHO KINASE INHIBITORS | PERCIPIAD INC (US) | 2025-08-27 | — | — | EP | disclosed |
| US-12358928-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-12281149-B2 | Modulators of G-protein coupled receptors | CARMOT THERAPEUTICS, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20240383960-A1 | Modulators of G-Protein Coupled Receptors | CARMOT THERAPEUTICS INC. (US) | 2024-11-21 | — | — | US | disclosed |
| US-20240150376-A1 | Compounds, Compositions and Methods | DENALI THERAPEUTICS INC. (US) | 2024-05-09 | — | — | US | disclosed |
| CN-117980325-A | Modulators of G-protein coupled receptors | 卡莫特治疗学股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-8017602-B2 | N-(2-(2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethylamino)ethyl)-3-(phenethoxy)propanamide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy | ASTRAZENECA AB (SE) | 2011-09-13 | — | — | US | disclosed |
| US-8017602-B2 | N-(2-(2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethylamino)ethyl)-3-(phenethoxy)propanamide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy | ASTRAZENECA AB (SE) | 2011-09-13 | — | — | US | disclosed |
| CN-102124003-A | Benzoxazinone derivatives as beta 2 adrenoreceptor antagonists for the treatment of respiratory diseases | ASTRAZENECA AB | 2011-07-13 | — | — | CN | disclosed |
| EP-2303873-A1 | BENZOXAZINONE DERIVATIVES ACTING AS BETA2-ADRENORECEPTOR AGONIST FOR THE TREATMENT OF RESPIRATORY DISORDERS | AstraZeneca AB (SE) | 2011-04-06 | — | — | EP | disclosed |
| US-20100105642-A1 | NOVEL COMPOUNDS 409 | ASTRAZENECA AB (SE) | 2010-04-29 | — | — | US | disclosed |
| US-20100105642-A1 | NOVEL COMPOUNDS 409 | ASTRAZENECA AB (SE) | 2010-04-29 | — | — | US | disclosed |
| US-20100105642-A1 | NOVEL COMPOUNDS 409 | ASTRAZENECA AB (SE) | 2010-04-29 | — | — | US | disclosed |
| WO-2009154557-A1 | BENZOXAZINONE DERIVATIVES ACTING AS BETA2-ADRENORECEPTOR AGONIST FOR THE TREATMENT OF RESPIRATORY DISORDERS | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009154557-A1 | BENZOXAZINONE DERIVATIVES ACTING AS BETA2-ADRENORECEPTOR AGONIST FOR THE TREATMENT OF RESPIRATORY DISORDERS | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | WO | disclosed |
| CN-101365694-A | Heterocycle-substituted 3-alkyl azetidine derivatives | MERCK & CO INC (US) | 2009-02-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383960-A1 | Modulators of G-Protein Coupled Receptors | GIPR, GLP1R, GCGR | HSP90AB1 2250/4885CYP4F2 4639/4885CYP4A11 3960/4885 |
| US-20260116848-A1 | Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists | GLP1R, GIPR, CCKBR | HSP90AB1 3202/4885CYP4F2 3190/4885CYP4A11 2559/4885 |
| US-20250388601-A1 | Compounds, Compositions and Methods | AURKC, WEE2, ERBB2 | HSP90AB1 1837/4885CYP4F2 1162/4885CYP4A11 259/4885 |
| US-20240150376-A1 | Compounds, Compositions and Methods | PIK3CA, PLK1, PIK3CB | HSP90AB1 789/4885CYP4F2 3465/4885CYP4A11 2526/4885 |
| US-20100105642-A1 | NOVEL COMPOUNDS 409 | GPR119, CYP4B1, CYP4A11 | HSP90AB1 2748/4885CYP4F2 108/4885CYP4A11 3/4885 |
| US-12358928-B2 | Compounds, compositions and methods | PIK3CA, PLK1, PIK3CB | HSP90AB1 789/4885CYP4F2 3465/4885CYP4A11 2526/4885 |
| US-12281149-B2 | Modulators of G-protein coupled receptors | GIPR, GLP1R, GCGR | HSP90AB1 2220/4885CYP4F2 4667/4885CYP4A11 3958/4885 |
| US-20260125401-A1 | BORON-CONTAINING RHO KINASE INHIBITORS | NTRK2, GRK6, GRK1 | HSP90AB1 873/4885CYP4F2 4231/4885CYP4A11 3329/4885 |
| US-12479866-B2 | Boron-containing rho kinase inhibitors | ROCK1, ROCK2, RHOT2 | HSP90AB1 649/4885CYP4F2 4225/4885CYP4A11 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.