Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14549899 | 0.85 | NAMPT (0.53) | NAMPTALDH1A1HPGDMAPTLMNA | |
| SCHEMBL12194865 | 0.83 | NAMPT (0.52) | NAMPTALDH1A1HPGDMAPTHDAC1 | |
| SCHEMBL10233654 | 0.83 | NAMPT (0.52) | NAMPTALDH1A1HPGDMAPTGAA | |
| SCHEMBL22077519 | 0.82 | NAMPT (0.56) | NAMPTALDH1A1HPGDMAPTHDAC1 | |
| SCHEMBL15480837 | 0.81 | ALDH1A1 (0.44) | NAMPTALDH1A1HPGDMAPTGAA | |
| SCHEMBL15480834 | 0.81 | ALDH1A1 (0.44) | NAMPTALDH1A1HPGDMAPTGAA | |
| SCHEMBL15480835 | 0.81 | ALDH1A1 (0.44) | NAMPTALDH1A1HPGDMAPTGAA | |
| SCHEMBL15480836 | 0.81 | ALDH1A1 (0.44) | NAMPTALDH1A1HPGDMAPTGAA | |
| SCHEMBL749799 | 0.81 | NAMPT (0.50) | NAMPTALDH1A1HPGDMAPTLMNA | |
| SCHEMBL12194866 | 0.80 | NAMPT (0.49) | NAMPTALDH1A1L3MBTL1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033069-B | Novel irreversible Bruton's tyrosine kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-03-04 | — | — | CN | disclosed |