Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715572 | 1.00 | SLCO1B1 (0.37) | SLCO1B1ABCB11MEN1KMT2AKDM4C | |
| SCHEMBL29411851 | 0.92 | SLCO1B1 (0.37) | SLCO1B1ABCB11MEN1KMT2AKDM4C | |
| SCHEMBL19715614 | 0.92 | SLCO1B1 (0.37) | SLCO1B1ABCB11MEN1KMT2AKDM4C | |
| SCHEMBL19715752 | 0.90 | ABCB11 (0.35) | SLCO1B1ABCB11MEN1KMT2AKDM4C | |
| SCHEMBL19715615 | 0.85 | SLCO1B1 (0.38) | SLCO1B1ABCB11KDM4CABCC3ABCC4 | |
| SCHEMBL19715730 | 0.85 | KDM4C (0.32) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19715528 | 0.85 | NPC1 (0.34) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL29411818 | 0.85 | NPC1 (0.34) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19728936 | 0.82 | ABCB11 (0.32) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19728935 | 0.80 | ABCB11 (0.34) | SLCO1B1ABCB11KDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114601830-A | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109963843-B | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-03-11 | — | — | CN | disclosed |