Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715802 | 1.00 | SLCO1B1 (0.39) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29411793 | 0.92 | SLCO1B1 (0.39) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL19715468 | 0.92 | SLCO1B1 (0.39) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL19715601 | 0.85 | SLCO1B1 (0.36) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL27157558 | 0.83 | SLCO1B1 (0.33) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29922208 | 0.83 | SLCO1B1 (0.33) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL30452885 | 0.81 | SLCO1B1 (0.32) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29068035 | 0.81 | SLCO1B1 (0.32) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29068148 | 0.80 | SLCO1B1 (0.39) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL30453259 | 0.80 | SLCO1B1 (0.39) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249443-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2022-08-11 | — | — | US | disclosed |
| CN-114601830-A | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109963843-B | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249443-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.