Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498220 | 0.90 | APP (0.59) | HTR6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12497201 | 0.88 | APP (0.63) | HTR6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5766147 | 0.87 | HTR6 (0.58) | HTR6MAPTMEN1KMT2AHTT | |
| SCHEMBL28493360 | 0.85 | KAT2B (0.55) | HTR6MAPTCYP1A2CYP2C9MEN1 | |
| SCHEMBL22481564 | 0.83 | MAPT (0.68) | HTR6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6169109 | 0.82 | MAPT (0.66) | MAPTCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL20919464 | 0.82 | MAPT (0.58) | HTR6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12497420 | 0.80 | APP (0.54) | HTR6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29525978 | 0.80 | MAPT (0.53) | MAPTKMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL6182039 | 0.80 | MAPT (0.53) | MAPTKMT2AL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |