Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.72 |
| ▸ | MGAM | O43451 | 2/20 | 0.72 |
| ▸ | SI | P14410 | 2/20 | 0.72 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.72 |
| ▸ | POLD1 | P28340 | 3/20 | 0.69 |
| ▸ | POLN | Q7Z5Q5 | 3/20 | 0.69 |
| ▸ | POLK | Q9UBT6 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TCF4 | P15884 | 3/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726983 | 0.58 | CYP3A4 (0.57) | CYP3A4TDP1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL22799252 | 0.58 | CYP3A4 (0.66) | GAACYP3A4TDP1SMN1; SMN2ACHE | |
| SCHEMBL12242925 | 0.56 | POLD1 (0.40) | GAAMGAMSIMGAM2POLD1 | |
| Orsellinic Acid, Ethyl Ester SCHEMBL1648471 | 0.56 | CYP3A4 (1.00) | CYP3A4TDP1SMN1; SMN2ACHEMEN1 | |
| Methyl Orsellinate SCHEMBL370816 | 0.56 | CYP3A4 (1.00) | GAACYP3A4TDP1SMN1; SMN2ACHE | |
| SCHEMBL18570498 | 0.55 | CYP3A4 (0.67) | GAACYP3A4TDP1SMN1; SMN2ACHE | |
| SCHEMBL10610261 | 0.55 | CYP3A4 (0.67) | CYP3A4TDP1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL10727009 | 0.54 | CYP3A4 (0.60) | CYP3A4TDP1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL10722726 | 0.54 | CYP3A4 (0.81) | CYP3A4TDP1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL1129779 | 0.53 | CYP3A4 (0.67) | GAACYP3A4TDP1SMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362436-A | anti-PD-L1 antibodies and uses thereof | 桂林三金药业股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117062611-A | Chimeric Antigen Receptor (CAR) constructs and NK cells expressing the CAR constructs | 惠和生物技术(上海)有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-112424225-B | anti-PD-L1 antibodies and uses thereof | 桂林三金药业股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-108017880-B | Formable cork resistant to mold | 波音公司 | 2022-03-11 | — | — | CN | disclosed |