SCHEMBL1129779

SCHEMBL1129779

Cc1cc(O)cc(O)c1C(=O)OCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.67
TDP1 Q9NUW8 4/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
LMNA P02545 2/20 0.64
ACHE P22303 2/20 0.57
NR1H2 P55055 1/20 0.54
NR1H3 Q13133 1/20 0.54
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 4/20 0.52
HPGD P15428 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPK1 P28482 2/20 0.52
MEN1 O00255 2/20 0.52
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538283 0.92 LMNA (0.56) CYP3A4TDP1SMN1; SMN2LMNAKMT2A
SCHEMBL9741945 0.89 TDP1 (0.62) TDP1LMNANR1H2NR1H3KMT2A
SCHEMBL10610261 0.88 CYP3A4 (0.67) CYP3A4TDP1SMN1; SMN2LMNAACHE
SCHEMBL8053277 0.87 CYP3A4 (0.61) CYP3A4TDP1SMN1; SMN2LMNAACHE
SCHEMBL10612439 0.85 CYP3A4 (0.63) CYP3A4TDP1SMN1; SMN2LMNAACHE
SCHEMBL31638890 0.84 CA12 (0.52) CYP3A4TDP1SMN1; SMN2LMNAKMT2A
SCHEMBL31638730 0.84 TDP1 (0.53) CYP3A4TDP1SMN1; SMN2LMNAKMT2A
SCHEMBL19695761 0.83 TDP1 (0.64) CYP3A4TDP1LMNANR1H2NR1H3
SCHEMBL10727009 0.83 CYP3A4 (0.60) CYP3A4TDP1SMN1; SMN2LMNAACHE
SCHEMBL31638781 0.83 CYP3A4 (0.52) CYP3A4TDP1SMN1; SMN2LMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60180884-A None JP disclosed
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof LIFEMINE THERAPEUTICS, INC. 2025-07-17 US disclosed
WO-2025137084-A2 TRIESTER COMPOUNDS AND METHODS OF USE THEREOF LIFEMINE THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
WO-2025137071-A2 TRIESTER COMPOUNDS AND METHODS OF USE THEREOF LIFEMINE THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
EP-0219302-B2 Recording materials FUJI PHOTO FILM CO LTD (JP) 2000-06-28 EP disclosed
US-5827796-A Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-27 US disclosed
US-4791095-A ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1988-12-13 US disclosed
US-4771034-A LEUCO DYE, SALICYCLIC ACID DERIVATIVE AS ELECTRON ACCEPTOR FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed
US-4742041-A DYE PRECURSOR, PROTECTIVE COATING FUJI PHOTO FILM CO., LTD. (JP) 1988-05-03 US disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed
US-4728633-A HEAT AND PRESSURE SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1988-03-01 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4682193-A HEAT SENSITIVE, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
US-4628335-A BISHYDROXYCUMYLBENZENE COMPOUND AS COLOR DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1986-12-09 US disclosed
JP-S60180884-A RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1985-09-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof CYP46A1, CYP17A1, CYP27A1 CYP3A4 104/4885TDP1 1071/4885SMN1; SMN2 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.