Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | CASR | P41180 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306340 | 1.00 | CFTR (0.61) | CFTRCASRPOLBKDM4EMEN1 | |
| SCHEMBL29411951 | 0.89 | CFTR (0.72) | CFTRKDM4EMEN1KMT2ALMNA | |
| SCHEMBL10475864 | 0.86 | CFTR (0.52) | CFTRCASRPOLBKDM4EMEN1 | |
| SCHEMBL28381810 | 0.81 | CFTR (0.56) | CFTRKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6514222 | 0.80 | ALDH1A1 (0.59) | CFTRPOLBKDM4EMEN1KMT2A | |
| SCHEMBL29411968 | 0.80 | ALDH1A1 (0.64) | CFTRCASRKDM4EMEN1KMT2A | |
| SCHEMBL28484825 | 0.80 | ALDH1A1 (0.64) | CFTRCASRKDM4EMEN1KMT2A | |
| SCHEMBL28901986 | 0.79 | MEN1 (0.58) | CASRPOLBKDM4EMEN1KMT2A | |
| SCHEMBL29412050 | 0.79 | MEN1 (0.58) | CASRPOLBKDM4EMEN1KMT2A | |
| SCHEMBL6514322 | 0.79 | ALDH1A1 (0.62) | CFTRPOLBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |