Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435004 | 1.00 | BPTF (0.46) | BPTFKAT2AKAT2BHTTHDAC4 | |
| SCHEMBL31091773 | 0.72 | BRD4 (0.50) | BPTFKAT2AKAT2B | |
| SCHEMBL13652039 | 0.72 | DRD1 (0.46) | KMT2AMEN1KDM4EMAPT | |
| SCHEMBL14012482 | 0.72 | BRD4 (0.47) | BPTFKAT2AKAT2B | |
| SCHEMBL29575028 | 0.70 | L3MBTL1 (0.50) | HTTHDAC4HPGDKMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL28436422 | 0.70 | BRD4 (0.46) | BPTFKAT2AKAT2B | |
| Hydrochloric Acid SCHEMBL17912356 | 0.70 | BRD4 (0.46) | BPTFKAT2AKAT2B | |
| SCHEMBL24870219 | 0.70 | ACACB (0.45) | HDAC4ACACBL3MBTL1 | |
| SCHEMBL27314354 | 0.70 | KDM1A (0.50) | KAT2BKMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL27314351 | 0.70 | KDM1A (0.50) | KAT2BKMT2AL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499639-B | Pyrimidone derivatives and their use in pharmacy | 四川大学华西医院 | 2022-03-04 | — | — | CN | disclosed |