SCHEMBL29413780

SCHEMBL29413780

COc1ccc(C=Cc2ncncn2)cc1OC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
MAPT P10636 1/20 0.63
HPGD P15428 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CYP1A1 P04798 10/20 0.57
CYP1B1 Q16678 9/20 0.57
CYP1A2 P05177 4/20 0.57
TUBB4A P04350 1/20 0.57
TUBB P07437 1/20 0.57
TUBA3C P0DPH7 1/20 0.57
TUBA1B P68363 1/20 0.57
TUBA4A P68366 1/20 0.57
TUBB4B P68371 1/20 0.57
TUBB3 Q13509 1/20 0.57
TUBB2A Q13885 1/20 0.57
TUBB8 Q3ZCM7 1/20 0.57
TUBA3E Q6PEY2 1/20 0.57
TUBA1A Q71U36 1/20 0.57
TUBA1C Q9BQE3 1/20 0.57
TUBB6 Q9BUF5 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25244768 1.00 ALDH1A1 (0.63) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL28344655 0.85 ALDH1A1 (0.65) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL9431599 0.82 CYP1A1 (0.80) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL9586847 0.82 CYP1A1 (0.80) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL9173377 0.80 CYP1A1 (0.84) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL9173364 0.80 CYP1A1 (0.84) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL4888628 0.77 CYP1A2 (0.61) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL4888630 0.77 CYP1A2 (0.61) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL6241247 0.77 HPGD (1.00) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1
SCHEMBL6241242 0.77 HPGD (1.00) ALDH1A1MAPTHPGDSMN1; SMN2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024024889-A1 OPTICAL LAYERED BODY 住友化学株式会社 2024-02-01 WO disclosed
WO-2024024890-A1 OPTICAL LAMINATE 住友化学株式会社 2024-02-01 WO disclosed
WO-2022239767-A1 LAMINATE AND DISPLAY DEVICE 住友化学株式会社 2022-11-17 WO disclosed
WO-2022045103-A1 TWO-PART COMPOSITION FOR FORMATION OF POLARIZING FILM 住友化学株式会社 2022-03-03 WO disclosed
WO-2022045104-A1 TWO-COMPONENT POLYMERIZABLE LIQUID CRYSTAL COMPOSITION 住友化学株式会社 2022-03-03 WO disclosed