Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 12/20 | 0.50 |
| ▸ | GRN | P28799 | 2/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.47 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.47 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286453 | 1.00 | LONP1 (0.50) | LONP1GRNSORT1CTSLKDM4E | |
| SCHEMBL25286452 | 1.00 | LONP1 (0.50) | LONP1GRNSORT1CTSLKDM4E | |
| SCHEMBL9830710 | 0.84 | LONP1 (0.63) | LONP1CTSLKDM4EPSMB5PSMB11 | |
| SCHEMBL9830718 | 0.84 | LONP1 (0.63) | LONP1CTSLKDM4EPSMB5PSMB11 | |
| SCHEMBL22610053 | 0.82 | LONP1 (0.51) | LONP1CTSLKDM4EPSMB5PSMB11 | |
| SCHEMBL22610052 | 0.82 | LONP1 (0.51) | LONP1CTSLKDM4EPSMB5PSMB11 | |
| SCHEMBL28349151 | 0.82 | LONP1 (0.61) | LONP1GRNSORT1CTSLPSMB5 | |
| SCHEMBL2125178 | 0.82 | LONP1 (0.61) | LONP1GRNSORT1CTSLPSMB5 | |
| SCHEMBL13931851 | 0.81 | LONP1 (0.50) | LONP1CTSLKDM4EPSMB5PSMB11 | |
| SCHEMBL25223371 | 0.79 | LONP1 (0.48) | LONP1CTSLKDM4EPSMB5PSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043374-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | disclosed |