Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 10/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830710 | 1.00 | LONP1 (0.63) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL21968829 | 0.85 | FPR1 (0.56) | LONP1CTSL | |
| SCHEMBL21969646 | 0.85 | FPR1 (0.56) | LONP1CTSL | |
| SCHEMBL25286453 | 0.84 | LONP1 (0.50) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL25286452 | 0.84 | LONP1 (0.50) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL29414306 | 0.84 | LONP1 (0.50) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL22610052 | 0.84 | LONP1 (0.51) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL22610053 | 0.84 | LONP1 (0.51) | LONP1HTTSMN1; SMN2KDM4ECTSL | |
| SCHEMBL25286304 | 0.83 | LONP1 (0.49) | LONP1KDM4ECTSLPSMB5PSMB11 | |
| SCHEMBL25286303 | 0.83 | LONP1 (0.49) | LONP1KDM4ECTSLPSMB5PSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |