Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742332 | 1.00 | CYP2A6 (0.69) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL1530170 | 0.85 | CYP2A6 (0.50) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL4255979 | 0.83 | CYP2A6 (0.71) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL3576292 | 0.81 | CYP2A6 (1.00) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL2217042 | 0.81 | CYP2A6 (0.69) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL31588788 | 0.80 | CYP2A6 (0.67) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL4418009 | 0.79 | CYP2A6 (0.71) | CYP2A6CA2KEAP1NFE2L2MAPT | |
| SCHEMBL8547530 | 0.79 | CYP2A6 (0.75) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL13009558 | 0.78 | CYP2A6 (0.46) | CYP2A6CA2HDAC10HDAC11HDAC8 | |
| SCHEMBL7146984 | 0.78 | CA2 (0.55) | CYP2A6CA2KEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102541-B | Compounds as NMT inhibitors and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-116102541-A | Compounds as NMT inhibitors and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114174283-B | Compounds as NMT inhibitors and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114174283-A | Compounds as NMT inhibitors and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2022-03-11 | — | — | CN | disclosed |