Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.72 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946516 | 0.84 | HTR6 (0.74) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL2132873 | 0.83 | HTR6 (0.72) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL945595 | 0.83 | HTR6 (0.72) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL12700490 | 0.83 | HTR6 (0.72) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL16375238 | 0.82 | HTR6 (0.79) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL5726115 | 0.81 | HTR6 (0.69) | HTR6 | |
| SCHEMBL12641311 | 0.81 | HTR6 (0.69) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL27936448 | 0.81 | HTR6 (0.77) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL15250049 | 0.81 | HTR6 (1.00) | HTR6ALK | |
| SCHEMBL5726304 | 0.80 | HTR6 (0.72) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965884-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |