Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207859 | 1.00 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207857 | 1.00 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL22736917 | 0.92 | RIPK1 (0.85) | RIPK1 | |
| SCHEMBL22737135 | 0.92 | RIPK1 (0.85) | RIPK1 | |
| SCHEMBL17312455 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL17312459 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207598 | 0.84 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207701 | 0.84 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207594 | 0.84 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL23337243 | 0.84 | RIPK1 (0.77) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867548-B | RIP1K inhibitors | 里格尔药品股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-114437105-B | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2024-10-11 | — | — | CN | disclosed |
| EP-4126864-A1 | RIP1K INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-114437105-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-109071504-B | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2022-03-08 | — | — | CN | disclosed |