SCHEMBL29415684

SCHEMBL29415684

CN1C(=O)[C@H](NC(=O)c2cc(Cc3ccccc3)[nH]n2)[C@@H]2C[C@@H]2c2cccnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19880649 1.00 RIPK1 (1.00) RIPK1
SCHEMBL29415680 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19879532 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224591 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224430 1.00 RIPK1 (1.00) RIPK1
SCHEMBL29415785 1.00 RIPK1 (1.00) RIPK1
SCHEMBL29415661 1.00 RIPK1 (1.00) RIPK1
SCHEMBL20904060 1.00 RIPK1 (1.00) RIPK1
SCHEMBL22509127 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224425 1.00 RIPK1 (1.00) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071504-B Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2022-03-08 CN disclosed