SCHEMBL29415871

SCHEMBL29415871

CN1C(=O)[C@@H](NC(=O)c2cn(Cc3ccccc3)nn2)[C@H]2C[C@H]2c2nccnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19805443 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224698 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19228632 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224699 1.00 RIPK1 (1.00) RIPK1
SCHEMBL20050221 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19224461 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19228631 1.00 RIPK1 (1.00) RIPK1
SCHEMBL19228282 0.86 RIPK1 (0.75) RIPK1
SCHEMBL19805364 0.84 RIPK1 (0.73) RIPK1
SCHEMBL19255799 0.84 RIPK1 (0.73) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114437105-A Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2022-05-06 CN disclosed
CN-109071504-B Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2022-03-08 CN disclosed