Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | CALCR | P30988 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462076 | 0.87 | MAPK8 (0.63) | MAPK8MAPK9MAPK10KDM1AKEAP1 | |
| SCHEMBL30607472 | 0.86 | KDM1A (0.57) | MAPK8MAPK9MAPK10KDM1AKEAP1 | |
| SCHEMBL30804679 | 0.86 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL30607434 | 0.85 | MAPK8 (0.66) | MAPK8MAPK9MAPK10KDM1AKEAP1 | |
| SCHEMBL31462001 | 0.85 | MAPK8 (0.61) | MAPK8MAPK9MAPK10KDM1AKEAP1 | |
| SCHEMBL31462119 | 0.84 | MAPK8 (0.60) | MAPK8MAPK9MAPK10KDM1AKEAP1 | |
| SCHEMBL30607405 | 0.84 | NPY2R (0.60) | MAPK8MAPK9MAPK10KEAP1CALCR | |
| SCHEMBL29949610 | 0.84 | KDM1A (0.65) | MAPK8MAPK9MAPK10KDM1ACALCR | |
| SCHEMBL31461991 | 0.83 | MAPK8 (0.61) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL30437130 | 0.83 | MAPK8 (0.65) | MAPK8MAPK9MAPK10KDM1AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381984-B | Compositions and methods for improving sexual function | 尼莫克斯股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4275688-A2 | METHOD OF AMELIORATING OR PREVENTING THE WORSENING OR THE PROGRESSION OF SYMPTOMS OF BPH | Nymox Corporation (BS) | 2023-11-15 | — | — | EP | disclosed |
| CN-116785403-A | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-109310732-B | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114099636-A | Method of treating a condition requiring cell destruction or removal using peptides derived from neurofilament proteins | 尼莫克斯制药公司 | 2022-03-01 | — | — | CN | disclosed |