SCHEMBL29416612

SCHEMBL29416612

CON=CNC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
ORAI1 Q96D31 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802084 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL16661674 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL120159 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL12846200 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL120160 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL23979434 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL1797280 0.94 SMN1; SMN2 (0.33) KDM4EHTTSMN1; SMN2F2F10
SCHEMBL28721787 0.93 CA1 (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL12846257 0.93 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL12846202 0.92 PDK2 (0.34) KDM4ECA1CA2HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613426-A Pyripyropene derivative, composition and application thereof 青岛清原化合物有限公司 2025-03-14 CN disclosed
CN-114868755-B Insecticidal composition containing flucloxapyroxad and application thereof 海利尔药业集团股份有限公司 2023-10-24 CN disclosed
CN-114868755-A Insecticidal composition containing fluorine-containing chlorantraniliprole and application thereof 海利尔药业集团股份有限公司 2022-08-09 CN disclosed
CN-114573573-A Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-06-03 CN disclosed
CN-109068651-B Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-03-01 CN disclosed