SCHEMBL120160

SCHEMBL120160

CON=CNC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
ORAI1 Q96D31 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802084 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL29416612 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL16661674 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL120159 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL12846200 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL23979434 1.00 KDM4E (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL1797280 0.94 SMN1; SMN2 (0.33) KDM4EHTTSMN1; SMN2F2F10
SCHEMBL28721787 0.93 CA1 (0.32) KDM4ECA1CA2HTTRAB9A
SCHEMBL12846257 0.93 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL12846202 0.92 PDK2 (0.34) KDM4ECA1CA2HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4008329-B1 ISOXAZOLINE COMPOUNDS FOR USE IN TREATING DEMODICOSIS INTERVET INT BV (NL) 2025-06-11 EP claimed
EP-2833867-B2 SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS INTERVET INT BV (NL) 2023-05-10 EP claimed
US-11285101-B2 Soft chewable pharmaceutical products INTERVET INC. (US) 2022-03-29 US claimed
CN-107616168-B Aqueous suspension pesticide composition 日产化学工业株式会社 2021-12-03 CN claimed
CN-106659160-B Insecticidal or fungicidal composition and method for controlling plant diseases and pests 日产化学工业株式会社 2020-08-21 CN claimed
US-20190201332-A1 Soft Chewable Pharmaceutical Products INTERVET INC. (US) 2019-07-04 US claimed
EP-3079474-B1 ANTIPARASITIC USE OF ISOXAZOLINE COMPOUNDS INTERVET INT BV (NL) 2019-07-03 EP claimed
US-10321683-B2 Insecticidal, miticidal, nematicidal, molluscicidal, microbicidal, or bactericidal composition and method for controlling pest NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-06-18 US claimed
US-20180271095-A1 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-09-27 US claimed
EP-3255990-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2017-12-20 EP claimed
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION (US) 2012-06-14 US claimed
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 EP claimed
EP-2424347-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF Corporation (US) 2012-03-07 EP claimed
WO-2011147952-A1 PESTICIDAL MIXTURES BASF SE (DE) 2011-12-01 WO claimed
WO-2011025789-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF CORPORATION (US) 2011-03-03 WO claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE KDM4E 4540/4885CA1 929/4885CA2 1991/4885
US-11285101-B2 Soft chewable pharmaceutical products PAM, TAS2R46, TAS2R16 KDM4E 2334/4885CA1 1332/4885CA2 158/4885
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE KDM4E 2927/4885CA1 2387/4885CA2 2507/4885
US-20180271095-A1 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE PIK3C3, PMM2, PIR KDM4E 4135/4885CA1 2334/4885CA2 2861/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 KDM4E 1971/4885CA1 2289/4885CA2 2176/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 KDM4E 3406/4885CA1 2802/4885CA2 2561/4885
US-10321683-B2 Insecticidal, miticidal, nematicidal, molluscicidal, microbicidal, or bactericidal composition and method for controlling pest DDT, ACHE, DRD5 KDM4E 240/4885CA1 3995/4885CA2 1977/4885
US-20190201332-A1 Soft Chewable Pharmaceutical Products PAM, TAS2R46, TAS2R16 KDM4E 2334/4885CA1 1332/4885CA2 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.