Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678909 | 1.00 | MAOB (0.71) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19086304 | 0.90 | ABCG2 (0.78) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19086305 | 0.90 | ABCG2 (0.78) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25223496 | 0.86 | CYP3A4 (0.67) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25223485 | 0.86 | CYP3A4 (0.66) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25238512 | 0.86 | ACHE (0.81) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25204409 | 0.85 | CYP3A4 (0.65) | MAOBCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25266095 | 0.84 | ABCG2 (0.76) | MAOBMAPTMAPK1KMT2AABCG2 | |
| SCHEMBL25239854 | 0.84 | ACHE (0.81) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31233136 | 0.84 | ABCG2 (0.76) | MAOBMAPTMAPK1KMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105753-A | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2022-03-01 | — | — | CN | claimed |
| CN-114105753-B | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114105753-A | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2022-03-01 | — | — | CN | disclosed |