Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040849 | 1.00 | KMT2A (0.57) | KMT2AMEN1PKMNPSR1MAPT | |
| SCHEMBL23040986 | 0.89 | KMT2A (0.54) | KMT2AMEN1PKMMAPTLMNA | |
| SCHEMBL29760388 | 0.89 | KMT2A (0.54) | KMT2AMEN1PKMMAPTLMNA | |
| SCHEMBL23040969 | 0.85 | TLR7 (0.49) | KMT2AMEN1PKMMAPTLMNA | |
| SCHEMBL29417322 | 0.85 | TLR7 (0.49) | KMT2AMEN1PKMMAPTLMNA | |
| SCHEMBL10743840 | 0.84 | KMT2A (0.64) | KMT2AMEN1PKMMAPTLMNA | |
| SCHEMBL3783197 | 0.83 | F10 (0.68) | KMT2AMEN1PKMNPSR1MAPT | |
| SCHEMBL11538185 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL11240349 | 0.81 | MEN1 (0.57) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL8142651 | 0.78 | KMT2A (0.69) | KMT2AMEN1NPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144401-A | Novel quinazoline compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2022-03-04 | — | — | CN | disclosed |