SCHEMBL29417394

SCHEMBL29417394

O=C(CN(Cc1ccc(C(=O)O)cc1)Cc1cccc(C(=O)O)c1)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEP1B Q16820 20/20 1.00
▸ MEP1A Q16819 4/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19478225 1.00 MEP1B (1.00) MEP1BMEP1A
SCHEMBL31260551 0.94 MEP1B (1.00) MEP1BMEP1A
SCHEMBL19474709 0.94 MEP1B (1.00) MEP1BMEP1A
SCHEMBL19474736 0.94 MEP1B (1.00) MEP1BMEP1A
SCHEMBL19478233 0.91 MEP1B (1.00) MEP1BMEP1A
SCHEMBL19478270 0.91 MEP1B (1.00) MEP1BMEP1A
SCHEMBL31260504 0.91 MEP1B (1.00) MEP1BMEP1A
SCHEMBL29455576 0.91 MEP1B (1.00) MEP1BMEP1A
SCHEMBL19512593 0.91 MEP1B (1.00) MEP1BMEP1A
SCHEMBL31260525 0.91 MEP1B (1.00) MEP1BMEP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507175-B Novel inhibitors of hypnotins alpha and beta 维沃里翁治疗股份有限公司 2024-10-01 — — CN disclosed
CN-114507175-A Novel inhibitors of hypnotic proteins alpha and beta 维沃里翁治疗股份有限公司 2022-05-17 — — CN disclosed
CN-109195947-B Novel inhibitors of hypnotic proteins alpha and beta 维沃里翁治疗股份有限公司 2022-03-04 — — CN disclosed
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