SCHEMBL29417397

SCHEMBL29417397

O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
ACE P12821 3/20 0.55
FPR2 P25090 1/20 0.54
ITGB2 P05107 4/20 0.53
ICAM1 P05362 4/20 0.53
ITGAL P20701 4/20 0.53
NMBR P28336 2/20 0.52
MDM4 O15151 1/20 0.52
TP53 P04637 1/20 0.52
ECE1 P42892 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL850319 1.00 ALOX15 (0.56) ALOX15ACEFPR2ITGB2ICAM1
SCHEMBL29350138 1.00 ALOX15 (0.56) ALOX15ACEFPR2ITGB2ICAM1
SCHEMBL29350130 1.00 ALOX15 (0.56) ALOX15ACEFPR2ITGB2ICAM1
SCHEMBL119594 1.00 ALOX15 (0.56) ALOX15ACEFPR2ITGB2ICAM1
SCHEMBL119372 1.00 ALOX15 (0.56) ALOX15ACEFPR2ITGB2ICAM1
Water SCHEMBL6022940 0.99 ALOX15 (0.55) ALOX15ACEFPR2ITGB2ICAM1
Fluoride SCHEMBL7154596 0.99 ALOX15 (0.55) ALOX15ACEFPR2ITGB2ICAM1
SCHEMBL29903356 0.93 NMBR (0.55) ACENMBRECE1
SCHEMBL30310986 0.93 ACE (0.53) ACEECE1
SCHEMBL29903302 0.93 NMBR (0.55) ACENMBRECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211130-A1 NOVEL SAFRYLAMINE DERIVATIVES HAVING PRODRUG PROPERTIES COMPASS Pathfinder Limited (GB) 2023-07-19 EP claimed
CN-116075499-A Novel dephosphorylated galectin derivatives with prodrug properties 指南针探路者有限公司 2023-05-05 CN claimed
WO-2022053696-A1 NOVEL SAFRYLAMINE DERIVATIVES HAVING PRODRUG PROPERTIES COMPASS PATHFINDER LIMITED (GB) 2022-03-17 WO claimed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
CN-111655758-B Nucleic acid delivery polymers 国立大学法人东京大学 2024-03-22 CN disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 EP disclosed
CN-116640182-A Transdermal delivery system for polypeptides and related compounds 泰飞尔生物医药(苏州)有限公司 2023-08-25 CN disclosed
CN-116075499-A Novel dephosphorylated galectin derivatives with prodrug properties 指南针探路者有限公司 2023-05-05 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R ALOX15 3621/4885ACE 621/4885FPR2 190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.