SCHEMBL29417699

SCHEMBL29417699

CS(=O)(=O)N1CCN(c2cc(C(F)(F)F)ccc2CN2CCCC23CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC3)CC1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19582378 1.00 MGLL (0.68) MGLL
SCHEMBL19601707 0.91 MGLL (0.62) MGLL
SCHEMBL19582568 0.91 MGLL (0.64) MGLL
SCHEMBL19582493 0.90 MGLL (0.73) MGLL
SCHEMBL29417621 0.90 MGLL (0.73) MGLL
SCHEMBL19582689 0.90 MGLL (0.73) MGLL
SCHEMBL29417796 0.90 MGLL (0.73) MGLL
SCHEMBL29417629 0.90 MGLL (0.73) MGLL
SCHEMBL19582385 0.90 MGLL (0.73) MGLL
SCHEMBL19582563 0.89 MGLL (0.72) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109496213-B Spiro compounds and methods of making and using the same H.隆德贝克有限公司 2022-03-04 CN disclosed