Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.81 |
| ▸ | TUBB | P07437 | 4/20 | 0.81 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.81 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.81 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.81 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.81 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.81 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.81 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.81 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.81 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.81 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.81 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.81 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.81 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | P4HB | P07237 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530882 | 1.00 | TUBB4A (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12530451 | 1.00 | TUBB4A (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15046116 | 0.96 | TUBB4A (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14850594 | 0.96 | TUBB4A (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25854630 | 0.95 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25641508 | 0.95 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21124643 | 0.95 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20057090 | 0.95 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL836355 | 0.94 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13032760 | 0.94 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114158253-A | pHLIP targeted delivery of potent cytotoxic compounds | 罗德岛大学理事会 | 2022-03-08 | — | — | CN | disclosed |