SCHEMBL29418239

SCHEMBL29418239

CCN(C)C(=O)c1ccc2c(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)c(O)[nH]c2c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 15/20 0.85
MAP2K1 Q02750 3/20 0.64
MELK Q14680 2/20 0.61
AURKA O14965 1/20 0.61
RPS6KA5 O75582 1/20 0.61
RPS6KA4 O75676 1/20 0.61
FES P07332 1/20 0.61
ROS1 P08922 1/20 0.61
SLC2A1 P11166 1/20 0.61
LTK P29376 1/20 0.61
TYK2 P29597 1/20 0.61
PTK2 Q05397 1/20 0.61
PRKAA1 Q13131 1/20 0.61
PAK2 Q13177 1/20 0.61
PTK2B Q14289 1/20 0.61
BRSK2 Q8IWQ3 1/20 0.61
AURKB Q96GD4 1/20 0.61
STK26 Q9P289 1/20 0.61
STK24 Q9Y6E0 1/20 0.61
PDGFRB P09619 10/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720383 0.76 MELK (1.00) KDRMAP2K1MELKAURKARPS6KA5
Hydrochloric Acid SCHEMBL29943257 0.75 MELK (0.98) KDRMAP2K1MELKAURKARPS6KA5
SCHEMBL26928451 0.75 KDR (0.70) KDRMELKPDGFRBFGFR1FLT1
SCHEMBL26928536 0.74 KDR (0.61) KDRMAP2K1MELKAURKARPS6KA4
SCHEMBL26928496 0.72 KDR (0.84) KDRPDGFRBFGFR1FLT1FGFR3
SCHEMBL26928576 0.72 KDR (0.69) KDRPDGFRBFGFR1FLT1FGFR3
SCHEMBL30341852 0.71 MELK (1.00) KDRMELKPRKAA1PDGFRBFGFR1
SCHEMBL30197767 0.71 MAP2K5 (0.83) KDRMAP2K1MELKAURKARPS6KA4
SCHEMBL29374889 0.71 MAP2K5 (0.83) KDRMAP2K1MELKAURKARPS6KA4
SCHEMBL31046829 0.67 MAP2K5 (1.00) KDRMAP2K1MELKAURKARPS6KA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689064-A1 NON-CLONING METHODS OF BOVINE EMBRYO REPLICATION The Semex Alliance (CA) 2026-02-11 EP claimed
EP-4678739-A1 IN VITRO METHOD FOR OBTAINING CORTICAL BRAIN ORGANOIDS, CORTICAL BRAIN ORGANOIDS AND USES THEREOF Fundación Pública Andaluza Progreso Y Salud (ES) 2026-01-14 EP claimed
US-20250340837-A1 CELLS UNIVERSITY OF GENEVA (CH) 2025-11-06 US claimed
US-20250145948-A1 METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION Sumitomo Pharma Co., Ltd. (JP) 2025-05-08 US claimed
EP-4522186-A1 METHOD OF DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO RETINAL PIGMENT EPITHELIUM CELLS R.P. Scherer Technologies, LLC (US) 2025-03-19 EP claimed
EP-4504916-A1 CELLS University of Geneva (CH) 2025-02-12 EP claimed
CN-119325385-A Method for differentiating pluripotent stem cells into retinal pigment epithelial cells R.P.谢勒技术有限责任公司 2025-01-17 CN claimed
EP-4477746-A1 METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION Sumitomo Pharma Co., Ltd. (JP) 2024-12-18 EP claimed
CN-118765319-A Induced mature liver cell and preparation method thereof 清华大学 2024-10-11 CN claimed
WO-2024207103-A1 NON-CLONING METHODS OF BOVINE EMBRYO REPLICATION THE SEMEX ALLIANCE (CA) 2024-10-10 WO claimed
WO-2023160671-A1 INDUCIBLE MATURE LIVER CELL AND METHOD FOR PREPARING SAME 清华大学 2023-08-31 WO claimed
WO-2023153464-A1 METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION 住友ファーマ株式会社 2023-08-17 WO claimed
WO-2023104015-A1 METHOD FOR PROMOTING LONG-TERM STABLE PASSAGE OF PANCREATIC ISLET PRECURSOR CELLS 浙江大学 2023-06-15 WO claimed
CN-116103221-A Method for inducing somatic cell reprogramming into mammary epithelial cell by inhibiting ALKs 广西壮族自治区人民医院 2023-05-12 CN claimed
CN-112143758-B Method for preparing transgenic mammary gland bioreactor by using transdifferentiated mammary gland epithelial cells 广西大学 2023-04-21 CN claimed
WO-2023051685-A1 METHOD FOR AMPLIFYING ERYTHROID PROGENITORS OR ERYTHROBLASTS, AND APPLICATION THEREOF 北京大学 2023-04-06 WO claimed
CN-114317401-B Method for promoting long-term stable passage of islet precursor cells 浙江大学 2022-10-04 CN claimed
CN-114540278-A Microvessel in-vitro culture method and culture solution 青岛大学 2022-05-27 CN claimed
CN-114480253-A Culture medium for directional induced differentiation of pluripotent stem cells into hepatocytes, culture method and application 深圳市三启生物技术有限公司 2022-05-13 CN claimed
CN-114317401-A Method for promoting long-term stable passage of islet precursor cells 浙江大学 2022-04-12 CN claimed