Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826341 | 1.00 | DOT1L (0.61) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| Methane SCHEMBL29050649 | 0.98 | DOT1L (0.59) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL270025 | 0.86 | TERT (0.59) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL2163814 | 0.85 | NPC1 (0.72) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL27669172 | 0.84 | MAPT (0.48) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17335810 | 0.82 | DOT1L (0.63) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL19970705 | 0.81 | MAPT (0.73) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL483760 | 0.81 | MAPT (0.62) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL2682105 | 0.81 | MAPT (0.73) | DOT1LALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL16248321 | 0.80 | DOT1L (0.61) | DOT1LALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437147-B | Hypochlorous acid two-photon fluorescence probe HCP and preparation method and application thereof | 南京师范大学 | 2022-03-08 | — | — | CN | claimed |
| CN-110437147-B | Hypochlorous acid two-photon fluorescence probe HCP and preparation method and application thereof | 南京师范大学 | 2022-03-08 | — | — | CN | disclosed |