Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269700 | 1.00 | BTK (0.48) | BTKLCKGPR119HDAC4NAMPT | |
| SCHEMBL25267864 | 0.89 | BTK (0.49) | BTKLCK | |
| SCHEMBL29418369 | 0.89 | BTK (0.49) | BTKLCK | |
| SCHEMBL29418480 | 0.88 | BTK (0.48) | BTKLCKGPR119HDAC4NAMPT | |
| SCHEMBL25214221 | 0.88 | BTK (0.48) | BTKLCKGPR119HDAC4NAMPT | |
| SCHEMBL30599726 | 0.86 | BTK (0.48) | BTKLCK | |
| SCHEMBL29124651 | 0.86 | BTK (0.48) | BTKLCK | |
| Hydrochloric Acid SCHEMBL25246453 | 0.85 | BTK (0.53) | BTKLCK | |
| Hydrochloric Acid SCHEMBL29418446 | 0.85 | BTK (0.53) | BTKLCK | |
| SCHEMBL29124828 | 0.83 | BTK (0.47) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |