Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244549 | 1.00 | BTK (0.51) | BTKCYP46A1CRBNKLKB1KCNH2 | |
| SCHEMBL25214690 | 0.90 | BTK (0.51) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL29418616 | 0.90 | BTK (0.51) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL29418287 | 0.88 | BTK (0.54) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL25224811 | 0.88 | BTK (0.54) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL25267775 | 0.87 | BTK (0.50) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL29418315 | 0.87 | BTK (0.50) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL25211784 | 0.85 | BTK (0.46) | BTKCYP46A1 | |
| SCHEMBL29418518 | 0.85 | BTK (0.46) | BTKCYP46A1 | |
| SCHEMBL25249544 | 0.84 | BTK (0.46) | BTKCYP46A1CRBNKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |