SCHEMBL29419142

SCHEMBL29419142

Cn1cc(C(=O)Nc2ccc(F)cc2OC(F)(F)C(F)C(F)(F)F)c(C(F)F)n1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.41
DHODH Q02127 7/20 0.41
GPR6 P46095 3/20 0.40
MRGPRX1 Q96LB2 2/20 0.39
LMNA P02545 2/20 0.38
ALOX15 P16050 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
USP2 O75604 1/20 0.38
MAPT P10636 1/20 0.38
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232894 1.00 RECQL (0.41) RECQLDHODHGPR6MRGPRX1LMNA
SCHEMBL19458056 0.95 TSHR (0.42) RECQLDHODHGPR6MRGPRX1ALOX15
SCHEMBL374012 0.90 RECQL (0.43) RECQLDHODHLMNAALOX15MEN1
SCHEMBL2907876 0.89 MRGPRX1 (0.38) DHODHGPR6MRGPRX1ALOX15MEN1
SCHEMBL17673099 0.87 RECQL (0.39) RECQLDHODHMRGPRX1ALOX15MEN1
SCHEMBL21638776 0.86 DHODH (0.39) DHODHGPR6MRGPRX1LMNAMAPT
SCHEMBL17510947 0.84 MEN1 (0.38) RECQLDHODHGPR6MRGPRX1LMNA
SCHEMBL68046 0.83 TSHR (0.49) DHODHLMNAMEN1KMT2AMAPT
SCHEMBL29419112 0.83 TSHR (0.49) DHODHLMNAMEN1KMT2AMAPT
SCHEMBL28990887 0.82 DHODH (0.41) DHODHGPR6MRGPRX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384013-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2024-06-19 EP disclosed
EP-3525589-B1 4-ARYLAMINO SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE TO PROTECT CROPS BY FIGHTING UNDESIRED PHYTOPATHOGENIC MICOORGANISMS PI INDUSTRIES LTD (IN) 2023-12-06 EP disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples BAYER AKTIENGESELLSCHAFT (DE) 2023-04-25 US disclosed
EP-3556211-B1 ORGANIC AMMONIUM SALTS OF ANIONIC PESTICIDES CLARIANT INT LTD (CH) 2023-01-25 EP disclosed
WO-2022268520-A1 USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-12-29 WO disclosed
EP-4103554-A1 SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES FMC CORPORATION (US) 2022-12-21 EP disclosed
EP-4061798-A1 SOLVATES OF ABSCISIC ACID AND LIQUID COMPOSITIONS CONTAINING ABSCISIC ACID Clariant International Ltd (CH) 2022-09-28 EP disclosed
CN-115087639-A Substituted 5, 6-diphenyl-3 (2H) -pyridazinones for use as fungicides FMC公司 2022-09-20 CN disclosed
CN-114945558-A Fungicidal amides FMC公司 2022-08-26 CN disclosed
WO-2022128955-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES BAYER AKTIENGESELLSCHAFT (DE) 2022-06-23 WO disclosed
CN-114466836-A Solvates of abscisic acid and liquid compositions containing abscisic acid 科莱恩国际有限公司 2022-05-10 CN disclosed
CN-109561676-B Use of N-substituted pyrrolidones for promoting penetration of agrochemical active ingredients 科莱恩国际有限公司 2022-04-29 CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 CN disclosed
CN-109310082-B Timed release granular agrochemical composition and process for producing the same 拜耳农作物科学股份公司 2022-03-29 CN disclosed
CN-114158553-A Novel pesticide preparation and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples SACM1L, PPM1B, PSPH RECQL 810/4885DHODH 217/4885GPR6 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.