Sugi Predict

Sugi Predict / Compounds / SCHEMBL374012

SCHEMBL374012

SCHEMBL374012

Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)C(F)(F)F)c(C(F)F)n1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.43
▸ TSHR P16473 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ DHODH Q02127 6/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ MAPT P10636 2/20 0.40
▸ MEN1 O00255 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ IRAK4 Q9NWZ3 1/20 0.38
▸ TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19458056 0.93 TSHR (0.42) RECQLTSHRMAPK1ATMDHODH
SCHEMBL29419112 0.93 TSHR (0.49) TSHRMAPK1ATMDHODHKMT2A
SCHEMBL68046 0.93 TSHR (0.49) TSHRMAPK1ATMDHODHKMT2A
SCHEMBL29419142 0.90 RECQL (0.41) RECQLMAPK1DHODHKMT2AMAPT
SCHEMBL232894 0.90 RECQL (0.41) RECQLMAPK1DHODHKMT2AMAPT
SCHEMBL29779370 0.90 TSHR (0.42) TSHRMAPK1ATMDHODHKMT2A
SCHEMBL528778 0.90 TSHR (0.42) TSHRMAPK1ATMDHODHKMT2A
SCHEMBL11962977 0.88 TSHR (0.46) TSHRMAPK1ATMDHODHKMT2A
SCHEMBL672497 0.88 LMNA (0.53) RECQLTSHRMAPK1ATMDHODH
SCHEMBL29274932 0.87 LMNA (0.47) TSHRMAPK1ATMDHODHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230113346-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2023-04-13 — — US claimed
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 — — EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 — — US claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 — — EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 — — EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 — — EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 — — US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 — — US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 — — US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 — — US claimed
US-20100041682-A1 Ternary Pesticidal Mixtures BASF SE (DE) 2010-02-18 — — US claimed
US-20100029698-A1 Pesticidal Mixtures BASF SE (DE) 2010-02-04 — — US claimed
US-20100022389-A1 Pesticidal Mixtures BASF SE (DE) 2010-01-28 — — US claimed
US-20100016339-A1 FUNGICIDAL COMPOUNDS AND COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-01-21 — — US claimed
EP-2091330-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2009-08-26 — — EP claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 — — WO claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 — — WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 — — WO claimed
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides BASF SE (DE) 2008-10-16 — — US claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022389-A1 Pesticidal Mixtures AADAC, CTRL, AAAS RECQL 1089/4885TSHR 3382/4885MAPK1 4612/4885
US-20100029698-A1 Pesticidal Mixtures PTMS, THOP1, MLN RECQL 2943/4885TSHR 1138/4885MAPK1 4306/4885
US-20100016339-A1 FUNGICIDAL COMPOUNDS AND COMPOSITIONS CYP4F3, CBR3, CYP4B1 RECQL 3234/4885TSHR 1746/4885MAPK1 4128/4885
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides CBR3, CBR1, NAT1 RECQL 1908/4885TSHR 2622/4885MAPK1 3525/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC RECQL 2057/4885TSHR 989/4885MAPK1 2463/4885
US-20230113346-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB RECQL 270/4885TSHR 2256/4885MAPK1 1967/4885
US-20100041682-A1 Ternary Pesticidal Mixtures AADAC, AS3MT, DDT RECQL 1943/4885TSHR 3338/4885MAPK1 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.