Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314617 | 1.00 | PDE5A (1.00) | PDE5APDE6C | |
| SCHEMBL6443319 | 0.97 | PDE5A (0.94) | PDE5APDE6C | |
| SCHEMBL6441919 | 0.95 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL3680746 | 0.95 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL6446371 | 0.95 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL6444669 | 0.94 | PDE5A (0.89) | PDE5APDE6C | |
| SCHEMBL2148526 | 0.94 | PDE5A (0.89) | PDE5APDE6C | |
| SCHEMBL6446034 | 0.94 | PDE5A (0.89) | PDE5APDE6C | |
| SCHEMBL6445340 | 0.94 | PDE5A (0.88) | PDE5APDE6C | |
| SCHEMBL3680256 | 0.93 | PDE5A (0.88) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12465605-B2 | Methods and materials for gender-dependent treatment of cardiovascular dysfunction | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-11-11 | — | — | US | claimed |
| US-12465605-B2 | Methods and materials for gender-dependent treatment of cardiovascular dysfunction | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-11-11 | — | — | US | disclosed |
| US-20220211702-A1 | METHODS AND MATERIALS FOR GENDER-DEPENDENT TREATMENT OF CARDIOVASCULAR DYSFUNCTION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2022-07-07 | — | — | US | disclosed |
| CN-114144229-A | Methods and materials for gender-dependent treatment of cardiovascular dysfunction | 梅约医学教育与研究基金会 | 2022-03-04 | — | — | CN | disclosed |
| US-20220062307-A1 | METHODS AND MATERIALS FOR TREATING CALCIFIC AORTIC VALVE STENOSIS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-03-03 | — | — | US | disclosed |