SCHEMBL3680256

SCHEMBL3680256

CCc1c2nc(-c3cc(S(=O)(=O)N4CCN(O)CC4)cnc3OCCOC)[nH]c(=O)c2nn1Cc1ccccn1

nearest known ligand 0.88

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 20/20 0.88
PDE6C P51160 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148526 0.94 PDE5A (0.89) PDE5APDE6C
SCHEMBL314617 0.93 PDE5A (1.00) PDE5APDE6C
SCHEMBL29419599 0.93 PDE5A (1.00) PDE5APDE6C
SCHEMBL6442028 0.92 PDE5A (0.85) PDE5APDE6C
SCHEMBL6441919 0.92 PDE5A (0.90) PDE5APDE6C
SCHEMBL3680255 0.91 PDE5A (0.84) PDE5APDE6C
SCHEMBL6445340 0.91 PDE5A (0.88) PDE5APDE6C
SCHEMBL6443319 0.90 PDE5A (0.94) PDE5APDE6C
SCHEMBL2148340 0.90 PDE5A (0.81) PDE5APDE6C
SCHEMBL6443868 0.89 PDE5A (0.80) PDE5APDE6C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858599-B2 Enhancement of urogenital function HANDER ROBERT W 2010-12-28 US disclosed