Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Beminafil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beminafil SCHEMBL7124593 | 1.00 | PDE5A (0.44) | PDE5APDE11A | |
| Beminafil SCHEMBL29382322 | 1.00 | PDE5A (0.44) | PDE5APDE11A | |
| Beminafil SCHEMBL2421268 | 0.96 | PDE5A (0.47) | PDE5APDE11A | |
| Beminafil SCHEMBL29385559 | 0.96 | PDE5A (0.47) | PDE5APDE11A | |
| Beminafil SCHEMBL2421274 | 0.96 | PDE5A (0.47) | PDE5APDE11A | |
| Beminafil SCHEMBL6236544 | 0.95 | PDE5A (0.46) | PDE5APDE11A | |
| SCHEMBL6760546 | 0.90 | PDE5A (0.41) | PDE5APDE11A | |
| Beminafil SCHEMBL6236540 | 0.88 | PDE5A (0.41) | PDE5APDE11A | |
| SCHEMBL6763383 | 0.88 | PDE5A (0.42) | PDE5APDE11A | |
| SCHEMBL6764887 | 0.88 | MEN1 (0.40) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144229-A | Methods and materials for gender-dependent treatment of cardiovascular dysfunction | 梅约医学教育与研究基金会 | 2022-03-04 | — | — | CN | disclosed |