Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.63 |
| ▸ | KISS1R | Q969F8 | 7/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28235858 | 0.96 | ACE (0.57) | MC4R | |
| SCHEMBL29476543 | 0.95 | MC4R (0.68) | MC4RKISS1RGHSR | |
| SCHEMBL30028772 | 0.94 | MC4R (0.57) | MC4RKISS1R | |
| SCHEMBL13604887 | 0.94 | MC4R (0.57) | MC4RKISS1R | |
| SCHEMBL29672131 | 0.92 | NPY1R (0.56) | MC4RKISS1RGHSR | |
| SCHEMBL30919236 | 0.92 | KISS1R (0.55) | MC4RKISS1RGHSR | |
| SCHEMBL30919241 | 0.92 | KISS1R (0.55) | MC4RKISS1RGHSR | |
| SCHEMBL29476649 | 0.92 | MC4R (0.54) | MC4RKISS1R | |
| SCHEMBL29511119 | 0.92 | MC4R (0.54) | MC4RKISS1R | |
| SCHEMBL31249518 | 0.91 | MC4R (0.55) | MC4RKISS1RGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249797-B | GSDMD protein RFWK motif-based small molecule polypeptide drug and preparation method and application thereof | 南京医科大学 | 2024-01-23 | — | — | CN | claimed |
| CN-114249797-A | Small molecule polypeptide medicament based on GSDMD protein RFWK motif and preparation method and application thereof | 南京医科大学 | 2022-03-29 | — | — | CN | claimed |
| CN-114249797-B | GSDMD protein RFWK motif-based small molecule polypeptide drug and preparation method and application thereof | 南京医科大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-114249797-A | Small molecule polypeptide medicament based on GSDMD protein RFWK motif and preparation method and application thereof | 南京医科大学 | 2022-03-29 | — | — | CN | disclosed |