SCHEMBL29420173

SCHEMBL29420173

N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 1/20 0.49
BACE1 P56817 12/20 0.47
BACE2 Q9Y5Z0 2/20 0.46
CTSD P07339 2/20 0.44
MMP1 P03956 1/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8579953 0.97 NAALAD2 (0.47) NAALAD2BACE1BACE2CTSDMMP1
SCHEMBL30533108 0.94 BACE1 (0.55) BACE1BACE2CTSD
SCHEMBL30659882 0.93 BACE1 (0.57) BACE1BACE2CTSD
SCHEMBL31453841 0.93 DPP4 (0.39) NAALAD2BACE1BACE2CTSD
SCHEMBL30575178 0.92 NAALAD2 (0.51) NAALAD2BACE1BACE2
SCHEMBL30692727 0.91 MME (0.47)
SCHEMBL30578424 0.91 MME (0.47)
SCHEMBL31259942 0.91 MME (0.47)
SCHEMBL29577210 0.91 MME (0.47)
SCHEMBL17768459 0.91 DPP4 (0.40) NAALAD2BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115515617-A Diamine-linked receptor-specific cyclic peptides 帕拉丁科技公司 2022-12-23 CN disclosed
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R NAALAD2 1790/4885BACE1 1862/4885BACE2 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.