Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938874 | 0.86 | TDP1 (0.38) | ALDH1A1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL16755617 | 0.79 | TDP1 (0.43) | ALDH1A1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL24784695 | 0.73 | TSHR (0.43) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL29420175 | 0.73 | PTPN1 (0.37) | IDO1EGFRKDRABCG2 | |
| SCHEMBL29634606 | 0.73 | ALDH1A1 (0.46) | MTNR1AMTNR1BALDH1A1TDP1KMT2A | |
| SCHEMBL9321120 | 0.73 | ALDH1A1 (0.46) | MTNR1AMTNR1BALDH1A1TDP1KMT2A | |
| SCHEMBL4890429 | 0.73 | ALDH1A1 (0.46) | MTNR1AMTNR1BALDH1A1TDP1KMT2A | |
| SCHEMBL2450999 | 0.71 | ALDH1A1 (0.48) | MTNR1AMTNR1BALDH1A1TDP1KMT2A | |
| SCHEMBL14235312 | 0.71 | ALDH1A1 (0.43) | MTNR1AMTNR1BALDH1A1TDP1KMT2A | |
| SCHEMBL30803098 | 0.71 | ALDH1A1 (0.43) | MTNR1AMTNR1BALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163475-A | Catalyst system containing pyrrole-based rigid structure multi-site ligand, preparation method and application | 浙江智英石化技术有限公司 | 2022-03-11 | — | — | CN | disclosed |