SCHEMBL29420212

SCHEMBL29420212

C=C1[C@H](O)CC(=C/C=C2\CCC[C@]3(C)[C@@H]([C@@H](C)OC[C@H](C)C(C)(C)O)CC[C@@H]23)C[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ VDR P11473 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10125374 1.00 VDR (1.00) VDR
SCHEMBL13090316 1.00 VDR (1.00) VDR
SCHEMBL10125232 0.94 VDR (0.88) VDR
SCHEMBL10152497 0.90 VDR (0.81) VDR
SCHEMBL10125508 0.88 VDR (0.79) VDR
SCHEMBL10125254 0.88 VDR (0.79) VDR
SCHEMBL4168474 0.88 VDR (0.78) VDR
SCHEMBL19288068 0.86 VDR (0.77) VDR
SCHEMBL10125228 0.84 VDR (0.77) VDR
SCHEMBL18059298 0.84 VDR (0.77) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117901806-A Intelligent self-locking system based on vehicle body controller 苏州天浩汽车科技股份有限公司 2024-04-19 — — CN claimed
EP-4735431-A2 MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2026-05-06 — — EP disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 — — US disclosed
US-20260042788-A1 STAT6 COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-12 — — US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 — — EP disclosed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 — — US disclosed
EP-4674484-A2 THIENOPYRROLE COMPOUNDS Gilead Sciences, Inc. (US) 2026-01-07 — — EP disclosed
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2026-01-01 — — US disclosed
US-12503454-B2 LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2025-12-23 — — US disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 — — EP disclosed
US-20220323464-A1 COMPOSITION, FORMULATIONS AND METHODS OF MAKING AND USING BOTANICALS AND NATURAL COMPOUNDS FOR THE PROMOTION OF HEALTHY BRAIN AGING THE BRAIN HEALTH PROJECT, LLC 2022-10-13 — — US disclosed
WO-2022212194-A1 KHK INHIBITORS GILEAD SCIENCES, INC. (US) 2022-10-06 — — WO disclosed
EP-4058144-A1 TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF Gilead Sciences, Inc. (US) 2022-09-21 — — EP disclosed
WO-2022173722-A1 THIENOPYRROLE COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-08-18 — — WO disclosed
CN-114728168-A Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use 吉利德科学公司 2022-07-08 — — CN disclosed
WO-2022140326-A1 SUBSTITUTED INDOLE COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-06-30 — — WO disclosed
WO-2022140325-A1 6-SUBSTITUTED INDOLE COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-06-30 — — WO disclosed
US-20220149826-A1 AMPLITUDE MODULATION CIRCUIT AND SEMICONDUCTOR INTEGRATED CIRCUIT FOR OPTICAL COMMUNICATION SYSTEM SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2022-05-12 — — US disclosed
US-20220117979-A1 Composition, Formulations and Methods of Making and Using Botanicals and Natural Compounds for the Promotion of Healthy Brain Aging THE BRAIN HEALTH PROJECT LLC (US) 2022-04-21 — — US disclosed
US-11288869-B2 Information processing device, and information processing method SONY CORPORATION (JP) 2022-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042788-A1 STAT6 COMPOUNDS STAT6, IL6ST, NFATC1 VDR 1168/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 VDR 2582/4885
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 STAT6, NCOR1, NCOR2 VDR 477/4885
US-12503454-B2 LPA receptor antagonists and uses thereof LPAR1, LPAR2, LPAR4 VDR 475/4885
US-20260014147-A1 STAT6 DEGRADERS STAT6, NCOR1, CBR1 VDR 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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