SCHEMBL29421093

SCHEMBL29421093

C=C(C)CC(O)Nc1nc(SC)nc2nc[nH]c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ CXCR2 P25025 1/20 0.40
▸ HSP90AB1 P08238 3/20 0.39
▸ CDK2 P24941 3/20 0.38
▸ CDK1 P06493 2/20 0.38
▸ CCNB1 P14635 2/20 0.38
▸ CCNA2 P20248 2/20 0.38
▸ CCNA1 P78396 2/20 0.38
▸ MGMT P16455 1/20 0.38
▸ HIF1A Q16665 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ MAP3K5 Q99683 1/20 0.35
▸ XDH P47989 1/20 0.35
▸ ADORA1 P30542 3/20 0.34
▸ ADORA3 P0DMS8 2/20 0.34
▸ ADORA2A P29274 2/20 0.34
▸ POLA1 P09884 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372391 1.00 CYP1A2 (0.52) CYP1A2CYP3A4CYP2D6CYP2C19CXCR2
SCHEMBL17372571 0.79 CYP1A2 (0.55) CYP1A2CYP3A4CYP2D6CDK2HIF1A
SCHEMBL29421069 0.79 CYP1A2 (0.55) CYP1A2CYP3A4CYP2D6CDK2HIF1A
SCHEMBL101669 0.78 CYP3A4 (0.67) CYP1A2CYP3A4CYP2D6CYP2C19HSP90AB1
SCHEMBL31095955 0.78 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6CYP2C19CXCR2
SCHEMBL29404312 0.78 CYP3A4 (0.67) CYP1A2CYP3A4CYP2D6CYP2C19HSP90AB1
SCHEMBL546660 0.77 CYP1A2 (0.40) CYP1A2CYP3A4CXCR2CDK2CDK1
SCHEMBL28996831 0.76 CYP1A2 (0.55) CYP1A2CYP3A4CYP2D6CYP2C19CXCR2
SCHEMBL1524259 0.76 CYP1A2 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19HSP90AB1
SCHEMBL31012324 0.73 CYP2C19 (0.63) CYP1A2CYP3A4CYP2D6CYP2C19CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
WO-2025111452-A2 CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs PRIME MEDICINE, INC. (US) 2025-05-30 — — WO claimed
WO-2025111430-A1 CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL PRIME MEDICINE, INC. (US) 2025-05-30 — — WO claimed
WO-2025038963-A1 OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 — — CN claimed
CN-118076741-A Modified mRNA, modified non-coding RNA and uses thereof 布罗德研究所股份有限公司 2024-05-24 — — CN claimed
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 — — WO disclosed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
EP-4728076-A1 METHOD FOR STABILIZING RNA Pfizer Inc. (US) 2026-04-22 — — EP disclosed
EP-4720094-A1 MUTATED FRAGMENT OF VZV GLYCOPROTEIN E Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-08 — — EP disclosed
WO-2022152109-A2 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-07-21 — — WO disclosed
WO-2022152141-A2 POLYMER CONJUGATED LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-07-21 — — WO disclosed
WO-2022101461-A1 ENHANCED FORMULATION STABILIZATION AND IMPROVED LYOPHILIZATION PROCESSES BioNTech SE (DE) 2022-05-19 — — WO disclosed
CN-114391008-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-04-22 — — CN disclosed
CN-114206827-A Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
CN-114206463-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
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