SCHEMBL29421069

SCHEMBL29421069

C=C(C)CC(O)Nc1ncnc2nc[nH]c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.55
▸ HIF1A Q16665 1/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ CDK2 P24941 2/20 0.51
▸ LMNA P02545 5/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ HTT P42858 3/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ TSHR P16473 4/20 0.48
▸ RECQL P46063 1/20 0.48
▸ BRAF P15056 1/20 0.45
▸ TP53 P04637 1/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ PRMT1 Q99873 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372571 1.00 CYP1A2 (0.55) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL546660 0.82 CYP1A2 (0.40) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL17372391 0.79 CYP1A2 (0.52) CYP1A2HIF1ASMN1; SMN2CDK2CYP3A4
SCHEMBL29421093 0.79 CYP1A2 (0.52) CYP1A2HIF1ASMN1; SMN2CDK2CYP3A4
SCHEMBL31095854 0.75 CYP1A2 (0.57) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL101602 0.75 HTT (0.67) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL29359033 0.75 HTT (0.67) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL9204579 0.75 LMNA (0.66) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
Hydrochloric Acid SCHEMBL30150738 0.74 HTT (0.65) CYP1A2HIF1ASMN1; SMN2CDK2LMNA
SCHEMBL28996851 0.73 CYP1A2 (0.55) CYP1A2HIF1ASMN1; SMN2CDK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
WO-2025043082-A2 COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS THE BROAD INSTITUTE, INC. (US) 2025-02-27 — — WO claimed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
WO-2025038970-A1 MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 — — CN claimed
EP-4466074-A1 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF The Broad Institute Inc. (US) 2024-11-27 — — EP claimed
CN-118076741-A Modified mRNA, modified non-coding RNA and uses thereof 布罗德研究所股份有限公司 2024-05-24 — — CN claimed
EP-4314332-A2 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS ModernaTX, Inc. (US) 2024-02-07 — — EP claimed
WO-2023141474-A9 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2023-10-26 — — WO claimed
WO-2023141474-A1 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2023-07-27 — — WO claimed
WO-2022212711-A2 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS MODERNATX, INC. (US) 2022-10-06 — — WO claimed
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 — — WO disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
WO-2022152141-A2 POLYMER CONJUGATED LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-07-21 — — WO disclosed
CN-114391008-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-04-22 — — CN disclosed
CN-114206463-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
CN-114206827-A Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
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