SCHEMBL29421291

SCHEMBL29421291

CCCCOCCc1c(-c2ccccn2)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP19A1 P11511 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CBFB Q13951 10/20 0.38
▸ PDE5A O76074 3/20 0.35
▸ PDE4A P27815 3/20 0.35
▸ PDE4B Q07343 3/20 0.35
▸ PDE4C Q08493 3/20 0.35
▸ PDE4D Q08499 3/20 0.35
▸ NPC1 O15118 4/20 0.34
▸ RAB9A P51151 4/20 0.34
▸ RUNX1 Q01196 2/20 0.34
▸ GABRP O00591 1/20 0.33
▸ GABRD O14764 1/20 0.33
▸ GABRA1 P14867 1/20 0.33
▸ GABRB1 P18505 1/20 0.33
▸ GABRG2 P18507 1/20 0.33
▸ GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3522525 0.84 CBFB (0.40) CBFBNPC1RAB9ARUNX1METAP2
SCHEMBL28338004 0.80 CYP1A2 (0.39) CYP2D6CYP2C19CYP1A2CYP19A1CYP2C9
SCHEMBL31392583 0.78 CBFB (0.46) CBFBNPC1RAB9AMETAP2METAP1
SCHEMBL9582382 0.78 NPC1 (0.44) CBFBNPC1RAB9AMETAP2METAP1
SCHEMBL28347682 0.77 CBFB (0.44) CBFBNPC1RAB9ARUNX1METAP2
SCHEMBL28140534 0.76 CBFB (0.43) CBFBNPC1RAB9ARUNX1METAP2
SCHEMBL6009235 0.76 NPC1 (0.35) CBFBPDE4BPDE4DNPC1RAB9A
SCHEMBL28252316 0.75 STAT3 (0.45) CYP1A2PDE5AGABRPGABRDGABRA1
SCHEMBL27971649 0.74 STAT3 (0.44) CYP1A2PDE5AGABRPGABRDGABRA1
SCHEMBL28169160 0.74 STAT3 (0.42) PDE5APDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4603096-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE Biomimetix JV LLC (US) 2025-08-20 — — EP disclosed
EP-3606614-B1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE BIOMIMETIX JV LLC (US) 2025-05-21 — — EP disclosed
US-20250041314-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE BIOMIMETIX JV LLC (US) 2025-02-06 — — US disclosed
US-12171769-B2 Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure BIOMIMETIX JV, LLC (US) 2024-12-24 — — US disclosed
US-20220193090-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE BIOMIMETIX JV, LLC 2022-06-23 — — US disclosed
US-11285162-B2 Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure BIOMIMETIX JV, LLC (US) 2022-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193090-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE MRE11, XRCC5, RAD51 CYP2D6 3328/4885CYP2C19 3687/4885CYP1A2 2598/4885
US-20250041314-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING AND/OR PREVENTING A SIDE EFFECT ASSOCIATED WITH RADIATION AND/OR CHEMOTHERAPY EXPOSURE MRE11, XRCC5, RAD51 CYP2D6 3328/4885CYP2C19 3687/4885CYP1A2 2598/4885
US-11285162-B2 Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure MRE11, XRCC5, RAD51 CYP2D6 3328/4885CYP2C19 3687/4885CYP1A2 2598/4885
US-12171769-B2 Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure MRE11, XRCC5, RAD51 CYP2D6 3328/4885CYP2C19 3687/4885CYP1A2 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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