SCHEMBL29421900

SCHEMBL29421900

COc1cc(C)c(O)cc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.50
HMGCR P04035 2/20 0.48
CYP3A4 P08684 5/20 0.46
MAPT P10636 4/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 2/20 0.46
ALOX12 P18054 2/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
G6PD P11413 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
CCR6 P51684 1/20 0.46
HIF1A Q16665 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367766 0.87 CYP3A4 (0.50) CYP3A4MAPTKDM4EALDH1A1HPGD
SCHEMBL16328146 0.87 CYP3A4 (0.44) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL70697 0.87 CYP3A4 (0.50) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL879021 0.87 CYP3A4 (0.50) CYP3A4MAPTKDM4EALDH1A1HPGD
SCHEMBL1987450 0.83 HTT (0.58) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL30648558 0.83 HTT (0.58) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL29421892 0.82 MAOB (0.48) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL3674401 0.82 MAOB (0.48) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL23972589 0.81 ACHE (0.44) HTTHMGCRCYP3A4MAPTKDM4E
SCHEMBL93964 0.81 POLB (0.48) HTTCYP3A4MAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181047-A Method for preparing biphenol from cresol 中国科学院大连化学物理研究所 2022-03-15 CN claimed
CN-114181047-A Method for preparing biphenol from cresol 中国科学院大连化学物理研究所 2022-03-15 CN disclosed