SCHEMBL29421950

SCHEMBL29421950

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.54
▸ BACE1 P56817 11/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ OPRD1 P41143 1/20 0.45
▸ OPRK1 P41145 1/20 0.45
▸ GLO1 Q04760 1/20 0.44
▸ CTSD P07339 3/20 0.44
▸ PTPN1 P18031 4/20 0.44
▸ BACE2 Q9Y5Z0 1/20 0.42
▸ PTGS1 P23219 1/20 0.42
▸ GSTK1 Q9Y2Q3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421920 0.94 EGFR (0.48) EGFRBACE1OPRM1OPRD1OPRK1
SCHEMBL29421946 0.93 EGFR (0.52) EGFRBACE1OPRM1OPRD1OPRK1
SCHEMBL29350435 0.88 BACE1 (0.53) EGFRBACE1CTSDBACE2
SCHEMBL30140926 0.87 EGFR (0.49) EGFRBACE1OPRM1OPRD1OPRK1
SCHEMBL29422024 0.87 BACE1 (0.51) EGFRBACE1OPRM1OPRD1OPRK1
SCHEMBL29855833 0.87 PTGS1 (0.52) EGFRBACE1GLO1CTSDBACE2
SCHEMBL30170446 0.86 EGFR (0.44) EGFRGLO1PTGS1GSTK1
SCHEMBL29872215 0.85 PTPN1 (0.50) EGFRBACE1OPRD1CTSDPTPN1
SCHEMBL30563243 0.85 DPP4 (0.45) BACE1OPRM1OPRD1OPRK1GLO1
SCHEMBL29430832 0.85 DPP4 (0.50) EGFRBACE1OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof EYEBIO KOREA (KR) 2025-09-30 — — US disclosed
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 — — EP disclosed
EP-3974441-B1 PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2024-12-04 — — EP disclosed
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-10-24 — — US disclosed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 — — US disclosed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof VIP, FURIN, IAPP EGFR 1108/4885BACE1 584/4885OPRM1 4051/4885
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 EGFR 1239/4885BACE1 850/4885OPRM1 4016/4885
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 EGFR 1239/4885BACE1 850/4885OPRM1 4016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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