SCHEMBL29423362

SCHEMBL29423362

C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)CN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 4/20 0.47
▸ APLNR P35414 1/20 0.46
▸ OPRM1 P35372 6/20 0.43
▸ OPRK1 P41145 6/20 0.43
▸ F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802040 0.85 ACE (0.52) ACEAPLNROPRM1OPRK1F2
SCHEMBL30844396 0.84 ACE (0.46) ACEAPLNR
SCHEMBL29801911 0.84 ACE (0.52) ACEF2
SCHEMBL30844328 0.83 ACE (0.48) ACEAPLNROPRK1
SCHEMBL29801838 0.83 OPRM1 (0.52) ACEAPLNROPRM1OPRK1
SCHEMBL29801966 0.83 ACE (0.51) ACEOPRK1
SCHEMBL29801988 0.83 ACE (0.51) ACEOPRK1F2
SCHEMBL29801916 0.83 ACE (0.53) ACEOPRM1F2
SCHEMBL29423403 0.82 F2 (0.50) ACEAPLNROPRM1F2
SCHEMBL31031600 0.82 F2 (0.47) ACEAPLNROPRM1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220048988-A1 CELLS EXPRESSING ANTIBODIES TARGETING HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USING THE SAME CHILDREN'S NATIONAL MEDICAL CENTER 2022-02-17 — — US claimed
EP-4039710-B1 ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123 SANOFI SA (FR) 2026-03-25 — — EP disclosed
US-20250312475-A1 BIVALENT, BISPECIFIC BINDING PROTEINS FOR PREVENTION OR TREATMENT OF HIV INFECTION SANOFI (FR) 2025-10-09 — — US disclosed
EP-4536676-A2 METHODS FOR PURIFICATION OF MULTI-SPECIFIC ANTIBODIES Sanofi (FR) 2025-04-16 — — EP disclosed
CN-119343359-A Method for purifying multispecific antibodies 赛诺菲 2025-01-21 — — CN disclosed
CN-119291194-A Method for quantifying a polypeptide 建新公司 2025-01-10 — — CN disclosed
CN-110256569-B Dual variable region antibody-like binding proteins with exchange binding region orientation 赛诺菲 2025-01-07 — — CN disclosed
CN-111801580-B Method for quantifying a polypeptide 建新公司 2024-08-23 — — CN disclosed
US-20240279362-A1 TRISPECIFIC AND/OR TRIVALENT BINDING PROTEINS SANOFI (FR) 2024-08-22 — — US disclosed
CN-109476732-B Trispecific and/or trivalent binding proteins 赛诺菲 2024-03-22 — — CN disclosed
US-11739160-B2 PseudoFab-based multispecific binding proteins SANOFI (FR) 2023-08-29 — — US disclosed
EP-3443006-B1 TRISPECIFIC AND/OR TRIVALENT BINDING PROTEINS SANOFI SA (FR) 2023-08-02 — — EP disclosed
CN-109311966-B Trispecific and/or trivalent binding proteins for use in the prevention or treatment of HIV infection 赛诺菲 2023-03-10 — — CN disclosed
EP-4039710-A2 ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123 SANOFI (FR) 2022-08-10 — — EP disclosed
CN-114885609-A pseudo-Fab based multispecific binding proteins 赛诺菲 2022-08-09 — — CN disclosed
US-20220226495-A1 BIVALENT, BISPECIFIC BINDING PROTEINS FOR PREVENTION OR TREATMENT OF HIV INFECTION SANOFI (FR) 2022-07-21 — — US disclosed
US-20220119553-A1 TRISPECIFIC AND/OR TRIVALENT BINDING PROTEINS SANOFI (FR) 2022-04-21 — — US disclosed
CN-114230668-A anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 赛诺菲 2022-03-25 — — CN disclosed
CN-114230667-A anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 赛诺菲 2022-03-25 — — CN disclosed
US-20220048988-A1 CELLS EXPRESSING ANTIBODIES TARGETING HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USING THE SAME CHILDREN'S NATIONAL MEDICAL CENTER 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312475-A1 BIVALENT, BISPECIFIC BINDING PROTEINS FOR PREVENTION OR TREATMENT OF HIV INFECTION CD4, HAVCR2, TIMCC ACE 4153/4885APLNR 953/4885OPRM1 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback