Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.32 |
| ▸ | GNA15 | P30679 | 1/20 | 0.32 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16845898 | 1.00 | FFAR1 (0.47) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL23952803 | 1.00 | FFAR1 (0.47) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL18940288 | 1.00 | FFAR1 (0.47) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL29423916 | 0.92 | FFAR1 (0.42) | FFAR1CD274GNA15SLC10A1ABCC2 | |
| SCHEMBL18959404 | 0.90 | FFAR1 (0.52) | FFAR1CD274FFAR4GNA15SLC10A1 | |
| SCHEMBL18959460 | 0.90 | FFAR1 (0.35) | FFAR1CD274EGFRALKBH1 | |
| SCHEMBL16855673 | 0.87 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL29423892 | 0.87 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL16846007 | 0.87 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL16829648 | 0.87 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |