Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952766 | 0.92 | FFAR1 (0.42) | FFAR1CNR2PRKCQPRKCDPIM1 | |
| SCHEMBL16845954 | 0.92 | FFAR1 (0.42) | FFAR1CNR2PRKCQPRKCDPIM1 | |
| SCHEMBL23952822 | 0.88 | FFAR1 (0.43) | FFAR1CNR2PIM1PIM2ABL1 | |
| SCHEMBL18959463 | 0.88 | PRKCQ (0.37) | FFAR1CNR2PRKCQPRKCDPIM1 | |
| SCHEMBL29423913 | 0.84 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL29423891 | 0.81 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL29423955 | 0.80 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL23952770 | 0.78 | FFAR1 (0.41) | FFAR1CNR2 | |
| SCHEMBL29423900 | 0.77 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL15474005 | 0.75 | FFAR1 (0.52) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |