Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GNA15 | P30679 | 1/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16846007 | 0.92 | FFAR1 (0.51) | FFAR1CD274FFAR4 | |
| SCHEMBL16855673 | 0.92 | FFAR1 (0.51) | FFAR1CD274FFAR4 | |
| SCHEMBL16829648 | 0.92 | FFAR1 (0.51) | FFAR1CD274FFAR4 | |
| SCHEMBL29423892 | 0.92 | FFAR1 (0.51) | FFAR1CD274FFAR4 | |
| SCHEMBL15474005 | 0.91 | FFAR1 (0.52) | FFAR1CYP11B1CYP11B2FFAR4 | |
| SCHEMBL29423916 | 0.88 | FFAR1 (0.42) | FFAR1CD274GNA15SLC10A1ABCC2 | |
| SCHEMBL18959445 | 0.88 | FFAR1 (0.39) | FFAR1CD274FFAR4 | |
| SCHEMBL29423913 | 0.87 | FFAR1 (0.43) | FFAR1CYP11B1CYP11B2FFAR4 | |
| SCHEMBL15471471 | 0.85 | FFAR1 (0.54) | FFAR1FFAR4 | |
| SCHEMBL22474739 | 0.85 | FFAR1 (0.56) | FFAR1CYP11B1CYP11B2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |